| Judul | Impaired Mitochondrial Bioenergetics under Pathological Conditions / Giorgio Lenaz ; Salvatore Nesci (Edited by) |
| Pengarang | Lenaz, Giorgio Nesci, Salvatore |
| Penerbitan | Switzerland ; Basel : MDPI - Multidiciplinary Digital Publishing Institute, 2022 |
| Deskripsi Fisik | 460 p. :ilus., |
| ISBN | 978-3-0365-4647-6 |
| Subjek | MITOCHONDRIAL DYSFUNCTION MITOCHONDRIA |
| Catatan | Mitochondria are the powerhouses of cells; however, mitochondrial dysfunction causes energy depletion and cell death in a variety of diseases. Altered oxidative phosphorylation and ion homeostasis are associated with ROS production resulting from the disassembly of respiratory supercomplexes and the disruption of electron transfer chains. In pathological conditions, the dysregulation of mitochondrial homeostasis promotes Ca2+ overload in the matrix and ROS accumulation, which induces the mitochondrial permeability transition pore formation responsible for mitochondrial morphological changes linked to membrane dynamics, and ultimately, cell death. Finally, studies on the impaired mitochondrial bioenergetics in pathology could provide molecular tools to counteract diseases associated with mitochondrial dysfunction. |
| Bentuk Karya | Tidak ada kode yang sesuai |
| Target Pembaca | Tidak ada kode yang sesuai |
| Lokasi Akses Online |
https://www.mdpi.com/books/reprint/5829-impaired-mitochondrial-bioenergetics-under-pathological-conditions |
| No Barcode | No. Panggil | Akses | Lokasi | Ketersediaan |
|---|---|---|---|---|
| 283726192 | 616.07 Imp | Baca Online | Perpustakaan Pusat - Online Resources Ebook |
Tersedia |
| Tag | Ind1 | Ind2 | Isi |
| 001 | INLIS000000000169153 | ||
| 005 | 20260610111928 | ||
| 007 | ta | ||
| 008 | 260610################|##########|#|## | ||
| 020 | # | # | $a 978-3-0365-4647-6 |
| 035 | # | # | $a 0010-0626000398 |
| 082 | # | # | $a 616.07 |
| 084 | # | # | $a 616.07 Imp |
| 245 | # | # | $a Impaired Mitochondrial Bioenergetics under Pathological Conditions /$c Giorgio Lenaz ; Salvatore Nesci (Edited by) |
| 260 | # | # | $a Switzerland ; Basel :$b MDPI - Multidiciplinary Digital Publishing Institute,$c 2022 |
| 300 | # | # | $a 460 p. : $b ilus., |
| 505 | # | # | $a Mitochondria are the powerhouses of cells; however, mitochondrial dysfunction causes energy depletion and cell death in a variety of diseases. Altered oxidative phosphorylation and ion homeostasis are associated with ROS production resulting from the disassembly of respiratory supercomplexes and the disruption of electron transfer chains. In pathological conditions, the dysregulation of mitochondrial homeostasis promotes Ca2+ overload in the matrix and ROS accumulation, which induces the mitochondrial permeability transition pore formation responsible for mitochondrial morphological changes linked to membrane dynamics, and ultimately, cell death. Finally, studies on the impaired mitochondrial bioenergetics in pathology could provide molecular tools to counteract diseases associated with mitochondrial dysfunction. |
| 650 | # | # | $a MITOCHONDRIA |
| 650 | # | # | $a MITOCHONDRIAL DYSFUNCTION |
| 700 | 1 | # | $a Lenaz, Giorgio |
| 700 | 1 | # | $a Nesci, Salvatore |
| 856 | # | # | $a https://www.mdpi.com/books/reprint/5829-impaired-mitochondrial-bioenergetics-under-pathological-conditions |
| 990 | # | # | $a 283726192 |
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