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Judul Paediatric Formulation: Design and Development / Editors Nunzio Denora
Pengarang Denora, Nunzio (edit)
Penerbitan Basel, Switzerland : MDPI Books, 2021
Deskripsi Fisik 205p. :ill.
ISBN 978-3-0365-0741-5
Subjek RESEARCH-DESIGN
PEDIATRICS--RESEARCH
Abstrak The development of paediatric medicines can be challenging since this is a different patient population with specific needs. A medicine designed for use in paediatric patients must consider the following aspects: patient population variability; the need for dose flexibility; route of administration; patient compliance; excipient tolerability. For example, the toxicity of excipients may differ in children compared to adults and children have different taste preferences. Globally, about 75% of drugs do not carry regulatory approval for use in children; worldwide, many medications prescribed for the treatment of paediatric diseases are used off-label, and less than 20% of package inserts have sufficient information for treating children. This book provides an update on both state-of-the-art methodology and operational challenges in paediatric formulation design and development. It aims at re-evaluating what is needed for more progress in the design and development of age-appropriate treatments for paediatric diseases, focusing on: formulation development; drug delivery design; efficacy, safety, and tolerability of drugs and excipients.
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Lokasi Akses Online https://www.mdpi.com/books/reprint/3873-paediatric-formulation-design-and-development
https://mdpi-res.com/bookfiles/book/3873/Paediatric_Formulation_Design_and_Development.pdf?v=1753059867

 
No Barcode No. Panggil Akses Lokasi Ketersediaan
531725192 618.92 Den p Baca Online Perpustakaan Pusat - Online Resources
Ebook
Tersedia
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100 0 # $a Denora, Nunzio (edit)
245 1 # $a Paediatric Formulation: Design and Development /$c Editors Nunzio Denora
260 # # $a Basel, Switzerland :$b MDPI Books,$c 2021
300 # # $a 205p. : $b ill.
520 # # $a The development of paediatric medicines can be challenging since this is a different patient population with specific needs. A medicine designed for use in paediatric patients must consider the following aspects: patient population variability; the need for dose flexibility; route of administration; patient compliance; excipient tolerability. For example, the toxicity of excipients may differ in children compared to adults and children have different taste preferences. Globally, about 75% of drugs do not carry regulatory approval for use in children; worldwide, many medications prescribed for the treatment of paediatric diseases are used off-label, and less than 20% of package inserts have sufficient information for treating children. This book provides an update on both state-of-the-art methodology and operational challenges in paediatric formulation design and development. It aims at re-evaluating what is needed for more progress in the design and development of age-appropriate treatments for paediatric diseases, focusing on: formulation development; drug delivery design; efficacy, safety, and tolerability of drugs and excipients.
650 # # $a PEDIATRICS--RESEARCH
650 # # $a RESEARCH-DESIGN
856 # # $a https://mdpi-res.com/bookfiles/book/3873/Paediatric_Formulation_Design_and_Development.pdf?v=1753059867
856 # # $a https://www.mdpi.com/books/reprint/3873-paediatric-formulation-design-and-development
990 # # $a 531725192
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